Journal of Cardiovascular Echography

: 2020  |  Volume : 30  |  Issue : 5  |  Page : 26--32

Valvular damage

Ines Paola Monte1, Matteo Cameli2, Valentina Losi3, Fiorella Privitera1, Rodolfo Citro4 
1 Department of General Surgery and Medical-Surgery Specialities, University of Catania, AOU Policlinico Vittorio Emanuele, Catania, Italy
2 Department of Cardiovascular Diseases, University of Siena, Siena, Italy
3 Department of Scienze Mediche, Chirurgiche e Tecnologie Avanzate, University of Catania, AOU Policlinico, Catania, Italy
4 Department of Heart, University Hospital of Salerno, Salerno, Italy

Correspondence Address:
Prof. Ines Paola Monte
Cardiology Unit AOU Policlinico, Pad 8, Via S. Sofia 76, Catania

Valvular heart diseases (VHD) may be observed in patients with cancer for several reasons, including preexisting valve lesions, radiotherapy, infective endocarditis, and secondary to the left ventricle dysfunction. The incidence of VHD is especially in younger survivors treated with thoracic radiation therapy for certain malignancies, such as Hodgkin's lymphoma and breast cancer. The mechanism of radiation-induced damage to heart valves is not clear and includes diffuse fibrocalcific thickening of the valve. VHD is commonly diagnosed after a long latent period, in the context of clinical symptoms, or suspected on the basis of a new murmur. The evaluation includes identification of anatomical valve abnormalities, valve dysfunction, and assessing the functional consequences of valve dysfunction on the ventricles. Echocardiography is the optimal imaging technique for diagnostic and therapeutic management. Cardiovascular magnetic resonance and computed tomography (CT) may be used to assess the severity of VHD, but cardiac CT is mainly useful for detecting extensive calcifications of the ascending aorta. Patients exposed to mediastinal radiotherapy and minimal valve dysfunction require follow-up of 2–3 years, with moderate valve disease yearly, with severe, should be assessed for valve surgery.

How to cite this article:
Monte IP, Cameli M, Losi V, Privitera F, Citro R. Valvular damage.J Cardiovasc Echography 2020;30:26-32

How to cite this URL:
Monte IP, Cameli M, Losi V, Privitera F, Citro R. Valvular damage. J Cardiovasc Echography [serial online] 2020 [cited 2021 Apr 18 ];30:26-32
Available from:;year=2020;volume=30;issue=5;spage=26;epage=32;aulast=Monte;type=0