Journal of Cardiovascular Echography

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 30  |  Issue : 3  |  Page : 140--145

Value of speckle tracking echocardiography for early detection of left ventricular dysfunction in patients with systemic lupus erythematosus


Shereen Ibrahim Farag1, Reda Biomy Bastawisy2, Mohamed Ahmed Hamouda1, Wael Anwer Hassib2, Hala Ahmed Wahdan2 
1 Department of Cardiology, Faculty of Medicine, Benha University, Benha, Egypt
2 Department of Cardiology, Faculty of Medicine, Kafer Elsheikh University, Kafer Elsheikh, Egypt

Correspondence Address:
Shereen Ibrahim Farag
Benha University Hospital, Farid Nada Street, Postal Code: 13512, Benha
Egypt

Background: Cardiac dysfunction due to systemic lupus erythematosus (SLE) may be subclinical, but those patients are at high risk for developing clinical heart failure. Aim: The aim of this study is to assess the role of speckle tracking echocardiography (STE) in the early detection of systolic dysfunction in SLE patients. Patients and Methods: This was a case–control study. Participants were subdivided into two groups: Group 1 included 50 SLE patients and Group 2 included 50 healthy controls. Clinical evaluation, echocardiography, tissue Doppler, and STE were performed. Results: Global longitudinal strain (GLS) was significantly reduced in SLE group (−18.95 ± 2.02 vs. −21.4 ± 2.1, P < 0.001). However, there was no significant difference in left ventricular ejection fraction between both groups (P = 0.801). There was a significant positive correlation between the disease duration and age (r = 0.480, P < 0.001), pulmonary artery systolic pressure (PASP) (r = 0.628, P < 0.001), and GLS (%) (r = 0.417, P = 0.012). There was also a significant positive correlation between the disease activity index and GLS (%) (r = 0.7, P < 0.001) and PASP (r = 0.522, P < 0.001). Conclusion: SLE group had GLS % lower than the control group, and this was statistically significant, denoting early systolic dysfunction. Longer duration and high SLE activity index significantly affect GLS. GLS is an excellent noninvasive tool for early detection of subclinical left ventricular systolic dysfunction in SLE patients.


How to cite this article:
Farag SI, Bastawisy RB, Hamouda MA, Hassib WA, Wahdan HA. Value of speckle tracking echocardiography for early detection of left ventricular dysfunction in patients with systemic lupus erythematosus.J Cardiovasc Echography 2020;30:140-145


How to cite this URL:
Farag SI, Bastawisy RB, Hamouda MA, Hassib WA, Wahdan HA. Value of speckle tracking echocardiography for early detection of left ventricular dysfunction in patients with systemic lupus erythematosus. J Cardiovasc Echography [serial online] 2020 [cited 2020 Nov 30 ];30:140-145
Available from: https://www.jcecho.org/article.asp?issn=2211-4122;year=2020;volume=30;issue=3;spage=140;epage=145;aulast=Farag;type=0