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REGISTRY OF ITALIAN SOCIETY OF ECHOCARDIOGRAPHY AND CARDIOVASCULAR IMAGING
Year : 2018  |  Volume : 28  |  Issue : 2  |  Page : 78-89

Bicuspid aortic valve registry of the Italian society of echocardiography and cardiovascular imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and study design


1 Heart Department, University Hospital “San Giovanni di Dio e Ruggi d'Aragona,” Salerno, Italy
2 Department of Cardiovascular Science, University Hospital “Ospedali Riuniti Ancona,” Ancona, Italy
3 Cardiology Department, Villa Sofia Hospital, Palermo, Italy
4 Cardiology Department Hospital of Cava de' Tirreni and Costa d'Amalfi, Cava de' Tirreni, Italy
5 Division of Rehabilitation Cardiology, Rehabilitation Hospital of High Specialization ORAS, Motta di Livenza, Italy
6 Cardiology Department, CMSR Veneto Medica, Altavilla Vicentina, Italy
7 Cardiology Department, Ca' Foncello Hospital, Treviso, Italy
8 Department of Cardiology, Hospital Policlinico of Bari, Bari, Italy
9 Cardiology Department, Portuense Hospital, Rome, Italy
10 Cardiology Department, University Hospital Città della Salute e della Scienza di Torino, Molinette Hospital, Turin, Italy
11 Cardiology Department, G. Mazzini Hospital, Teramo, Italy
12 Cardiology Department Echocardiography Laboratory, Department of Cardiothoracic and Vascular, Policlinico Vittorio Emanuele, Catania University, Catania, Italy
13 Department of Cardiology, University Hospital “Ospedali Riuniti di Foggia”, Foggia, Italy
14 Department of Cardiology, San Paolo University Hospital, Milan, Italy
15 Department of Clinical and Experimental Medicine and Pharmacology, University of Messina, Messina, Italy
16 Division of Cardiology, Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy

Correspondence Address:
Rodolfo Citro
Hearth Department, University Hospital “San Giovanni di Dio e Ruggi d'Aragona,” Heart Tower Room 810, Largo Città d'Ippocrate, Salerno 84131, Salerno
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcecho.jcecho_5_18

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Background: Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%–2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable clinical presentations, including aneurysmal dilation of the aortic root and/or ascending thoracic aorta, isthmic coarctation, aortic dissection, or wall rupture. Methods: The REgistro della Valvola Aortica Bicuspide della Società Italiana di ECocardiografia e CArdiovascular Imaging is a retrospective (from January 1, 2010)/prospective, multicenter, observational registry, expected to enroll 3000 patients with definitive diagnosis of BAV made by transthoracic and/or transesophageal echocardiography, computed tomography, cardiovascular magnetic resonance, or at surgery. Inclusion criteria were definitive diagnosis of BAV. Patients will be enrolled regardless of the presence and severity of aortic valve dysfunction or aortic vessel disease and the coexistence of other congenital cardiovascular malformations. Exclusion criteria were uncertain BAV diagnosis, impossibility of obtaining informed consent, inability to carry out the follow-up. Anamnestic, demographic, clinical, and instrumental data collected both at first evaluation and during follow-up will be integrated into dedicated software. The aim is to derive a data set of unselected BAV patients with the main purpose of assessing the current clinical presentation, management, and outcomes of BAV. Conclusions: A multicenter registry covering a large population of BAV patients could have a profound impact on the understanding of the natural history of this disease and could influence its management.


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