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REVIEW ARTICLE
Year : 2013  |  Volume : 23  |  Issue : 1  |  Page : 1-9

Pulmonary regurgitation after tetralogy of fallot repair: A diagnostic and therapeutic challenge


The Labatt Family Heart Center, the Hospital for Sick Children, University of Toronto. Toronto, ON, Canada

Correspondence Address:
Luc Mertens
The Labatt Family Heart Center, The Hospital for Sick Children, 555 University Avenue, Toronto, ON
Canada
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Source of Support: None, Conflict of Interest: The authors have no conflicts of interest to disclose.


DOI: 10.4103/2211-4122.117975

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Background: Pulmonary regurgitation is the key hemodynamically significant lesion in repaired tetralogy of Fallot contributing to progressive right ventricular (RV) dilatation and biventricular dysfunction. The timing for pulmonary valve replacement remains a controversial topic, and the decision to intervene depends on assessment of RV size and RV function. Objectives: This review aims to discuss the echocardiographic techniques that can be used to assess patients with pulmonary regurgitation after the repair of tetralogy of Fallot defect. While cardiac magnetic resonance (CMR) imaging is the clinical reference method, there is an important role of echocardiography in identifying patients with significant pulmonary regurgitation and assessing the RV size and function. The different echocardiographic techniques that can be used in this context are discussed. Newer techniques for assessing RV size and function include three-dimensional (3D) echocardiography, tissue Doppler and strain imaging. 3D RV volumetric reconstruction based on two-dimensional imaging is a promising new technique that could potentially replace CMR for RV volumetric assessment. Conclusions: Developments in echocardiographic techniques provide new insights into the impact of pulmonary regurgitation on RV structure and function. Echocardiography and CMR are complementary modalities and further research is required to define the optimal use of both techniques for this indication.


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